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References

http://www.webmd.com/diabetes/type-2-diabetes-guide/diabetes-causes#1 people with type 2 diabetes produce insulin; however, the insulin their pancreas secretes is either not enough or the body is unable to recognize the insulin and use it properly (insulin resistance ).

http://www.ncl.ac.uk/magres/research /diabetes/documents/ Diabetes-Reversaloftype2studyJune15.pdf Newcastle biomedicine - Magnetic Resonance Centre - Newcastle University - Further information on the research on Reversing Type 2 Diabetes.
http://www.webmd.com/diabetes/news/ 20110126/cdc-26-million-americans-have-diabetes#1 The CDC says about 26 million adult Americans have diabetes and that 79 million more have prediabetes, a condition that raises the risk of developing type 2 diabetes, heart disease, and stroke.
http://patient.info/health/diabetes-and-high-blood-pressure In the UK, about half of all people aged over 65, and about 1 in 4 of all middle-aged adults, have high blood pressure. It is less common in younger adults.
https://www.drugwatch.com/ actos/type-2-diabetes/ Patients with Type 2 diabetes have excess sugar in their blood, which can cause a number of complications, including nerve and kidney damage. The disease is usually treated with medication, but some come with serious side effects.
https://www.niddk.nih.gov/ health-information/diabetes/ types/prediabetes-insulin-resistance Insulin resistance increases the risk of developing type 2 diabetes and prediabetes. Prediabetes usually occurs in people who already have insulin resistance. Although insulin resistance alone does not cause type 2 diabetes, it often sets the stage for the disease by placing a high demand on the insulin-producing beta cells. In prediabetes, the beta cells can no longer produce enough insulin to overcome insulin resistance, causing blood glucose levels to rise above the normal range.
https://intensivedietarymanagement.com/ new-paradigm- insulin-resistance-t2d/ Then there is the central paradox of hepatic insulin resistance. Let me explain. Insulin has two major actions on the liver. Remember that insulin goes up when you eat. It tells the body to stop producing glucose in the liver (gluconeogenesis) because there is lots of glucose coming in from the stomach (food). This is mediate through the FOX01 pathway.The second major action in the liver is to increase the production of fat (De Novo Lipogenesis (DNL)). This is to deal with the incoming flood of glucose that the body cannot use right way. This is mediated through the SREBP-1c pathway.
https://www.niddk.nih.gov/health-information /diabetes/types/ prediabetes-insulin-resistance Over time, insulin resistance can lead to type 2 diabetes and prediabetes because the beta cells do not keep up with the bodys increased need for insulin. Without enough insulin, excess glucose builds up in the bloodstream, leading to diabetes, prediabetes, and other serious health disorders.

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